Spinal Astrocytes

• Origin: Human iPSC line

• Products

• 2M Viable Cells/Vial - Standard (BX-0650)

• 1M Viable Cells/Vial - Standard (BX-0650e)

• Contents: 1 vial of cells and corresponding BrainXell supplement

• Cryopreserved

Specifications

Marker Expression and Morphology: Spinal Astrocytes (BX-0650) express key astrocyte markers GFAP (green) and S100β (red) at >90% and exhibit mature process-bearing morphologies (shown here with a DAPI stain).

Labelling by the spinal-specific marker HOXB4 (red) with a Hoescht stain highlights the regional specificity of the Spinal Astrocytes.

Function: Spinal Astrocytes (BX-0650) promote mature motor neuron activity. Co-culturing motor neurons with spinal astrocytes promotes maximal calcium influx within 10 days.

Co-culture spinal astrocytes with motor neurons also accelerates the development of activity recorded by multi-electrode array.